JFIFJPhotoshop 3.08BIM.@New Classification Framework Identifies Tumor-Associated Bacteri720260511PSCIENMAGUAuthorNew Classification Framework Identifies Tumor-Associated Bacterial Effectors as Crucial Drivers of Tumor Biology and Immune Response Science@https://scienmag.com/new-classification-framework-identifies-tum© 2026 Sciencehttps://scienmag.com/In recent years, the discovery of bacteria within tumor microenvironments has transformed our understanding of cancer biology. Far beyond their established roles in the gut and respiratory tracts, these tumor-associated bacteria have emerged as influential agents in cancer onset, progression, and immune landscape modulation. While various studies have attempted to identify specific bacterial species enriched […]ScienceBioBiologyBiology'bacterial drivers of cancer progression!bacterial impact on tumor biology-bacterial influence on tumor microenvironment'bacterial role in cancer immune evasion!cancer immune response modulation!functional metagenomics in cancerimmune landscape and bacteria'metagenomic analysis of cancer bacteriamicrobial effectors in oncology)microbial functional repertoire in tumorstumor microbiome diversity$tumor-associated bacterial effectorsC    !'"#%%%),($+!$%$C   $$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$"5!1AQa"2q#BR3br)!1"QA2RBq ?hˋqi;?v{M2ĕぞ.[-D/BhWTÉ+]:km"mg-Ic?V1Yq$f.N5:nzeoV3U\81 8UIkIHJސ-/{4v+SFw${S/6^Q5%bI۴x&,VB$k ᗀYv"݈;TƵfn)KnSg4"{ծZ qP52셥xJ aH- +Ȣm雛91XϚU/Sñ"+6׎֖@ (Lu9J(g V$MT@]3lGF"ehAYD"Dc5֗l l$1}k*rrSm) $4L1`_S0JѣSKȿ+cr?Do}J3Cp/5 $d_#j-lh8n2++yj2NO#23L*صFsI^ګ, xG3aBGQcU0!Ӭ}4 nauf`މiR)Oz0چ^+5@)2VJJr 5@8+Vi. mѳ5nܧRR8溨秵+~Y}̺pM/4D ھ;K0X(IZ祚 \aM4=Ae]UܢY&V: Q8 Ʉ2\=?vkWEHmKV92mYZ ozavfULZ[%C3e1^Sn|acϓcZT⒄'-jGi/=EXjMhTrշ4j Z!຦֯yj=*;M&>)1siaC.+rD`,`_ZUi{,<gI\OP-'柷mYLkӫ6$Fi %)- wS}BB$`qRORˇыZ.\i(- d4 MsZF#n 1 +@e$١:b@qJ=+& _RE p4d\b˷8ĩ8Ҏ.m4do$w%+!#`~3Z )m3[S)+Q<Ý}Ipһۯ:tퟭ9}[ʢ'ƕPTbUr 6dk_D9 @jB-98PL%-}pO 1zESmA@(ӂs؟|'L7*;<%ҥ}9hЕsHY|⦝Ê*Ihjm)M>i2[J]sdNVk(CKq-}wF,FN [ie9bPTC  VSLa^fwSpVP 9,Bò%v:B0 !'u+zԦ@b]Y%*QW'ܝ 4=ͺÊK ~MJwIuø%-;^,xI9UC~pr7D[.:~,2~+p G|' rILj1* YDngrU8Ƕ8wWF/3VJ*_e}]AVY%AN!>@QȮ)85[>`zمK]YUn-#D ¨e#srp:[kB굛6Sr[Osq#jӑmrq%(Ü -{ .ɑ\uV$J1xs$pyê\qr{8U!Iy4?~8G"ϣ)He<Q7#=)vbbzDA$LI- (s uݢL[K\ $Bq NWPs; jBG{S|n2= ՜('nԖˌ(ܔ[i <Ԅ-a;|ڥZ>])cQPP* [PN0h@6GqA LCx")oI[$p}|!*-+uwnǟqAE6^LϺJV QU93bH9qj28;T qZp[tlB({ H0.[%,WObQbfL$ -ZnE^aA'z]M(-h:{N]NqPREE@8}@4 ;k8n%)>6n|E1+^iYk1 ǚkiمQI)Keh>+HblO"d**>и,mݟQ繢+M4g]J3!V& Dq Әh+y {Tj_},l0gruqІd';sY7ī/n[hap $OƧ!)aئcnp xNf0R)q0viNIl2+KdycK"?ֿlSBu-)Mdikk!7)!^9>_}ոG5'y&A3&E¥{}*RD{ڄ+20+NǖgFVNM%aցRZ*D9k8hB65,_ enS; |ӑٱXlQB^R FjSq\ExWIu6yo]u͡- 5VN2չ%M6sv>ܟR:xLX͏i)qXE΂RU[4SQ<:XYJkNTS6@+/EIOܟO \BPhճQ. @O+jM1TCJ+U,:}bيZp )\1DY}:#um<}ʇmn`7- ,|u0WtPMZ=9RH"IF4A*bRG4Ũ/MU%qQn(b=ʡď*5+d<@pSHHCs o>lx!^fmB[3Y G{uAxJN2I`%N(C[*)&C=@3lW^AC=z#%֭|yN :ii&F<WGvo]9$ԩV'Oi^ڥJ\nΥV,ܒyRhqJ: