JFIFPhotoshop 3.08BIMBMachine Learning Imaging Predicts Parkinson’s Genotype, Mitochon720260801PSCIENMAGUAuthornMachine Learning Imaging Predicts Parkinson’s Genotype, Mitochondrial-Lysosomal Abnormalities in iPS Neurons Science@https://scienmag.com/machine-learning-imaging-predicts-parkinson© 2026 Sciencehttps://scienmag.com/Parkinson’s disease may leave a visible signature in the laboratory long before its most familiar symptoms become obvious. In a study published in npj Parkinson’s Disease, Li, Powell, Chedid and colleagues report that machine-learning analysis of microscope images can predict the genetic background of Parkinson’s disease models and detect abnormalities linking two cellular systems at […]ScienceMedMedicineMedicineAcellular signatures of Parkinson’s disease in laboratory models4early biomarkers for Parkinson’s disease detection=genetic prediction of Parkinson’s disease from imaging data(genetic variants and cellular phenotypes?iPS cell-derived neurons for neurodegenerative disease modeling5machine learning-based image analysis in neuroscience:mitochondrial and lysosomal abnormalities in Parkinson’s4neural imaging analysis with artificial intelligence6Parkinson’s disease diagnosis using machine learning7role of mitochondria and lysosomes in neurodegeneration7stem cell technology for Parkinson’s disease researchC    !'"#%%%),($+!$%$C   $$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$">!1A"Qaq2BR#C$35br4s6!1AQaq"23#Br4Rb ?T)BJR;P(iWv-2z%+.u;pd)[:&ūYyZng%HKO腎~4DGPT";y`KK(XAW5&}eHڞPB|KKm/s[{eUC'vZhhWr4iJViG]4 ݾ-dzuMXr*GPI>]2Yf7-V8:^䈌nRWxO++ -ܒ6t~,gU0Ԥ)9Nמš ej\/z bl،*cuM\#?. CtW/;;=ܟVSYm :IV{'#g2?jѧC+bt!~OC^s)]F<=q{C]9kO.,[B1#+%"#Qxvs5 i|JR)JP*Nܿ^[_p$fcKks+i{ mmM/jJD?3Vn9z$iIu, `WZ 8k:'S'P_NfynCwEgDŽV SN~,>b;߼X MCQObv~Dfm( gYZXgAA$!ҲR?+ac1ӾS$cӍ):|sM'ycTb%= ʣ΀υAXUwwgi"w|\gP>;=uD3F޸jxbGE^YXPrE>!Uo㯥,D7 946FKn1/%MlPCi>7ҶVoA88b:[R"V*aÜMn`j[cr&5()v}7:--(|P@pYEv8<5/gmGq_x)_nQOB$?Yɂ4U,e(Y9ʞ#@?OU.f`qˍ|j{1nI9+!離qܶK$`i;e]XyRSUg [WzmiY+N_ڲmء ,h8q๕jaJ%^PgyѐnͦyC.`!}vPYSϨO3R"䶉 ' @Ƥَ۱Hc_n<Z}0m;xOt )RTy@&ge::܆(JJeڑ3K,CDڑOҬSK#b<|Qw|,Az!mt-\6Ff9 }q5ɩx#f/lo{;#Rdfua pQ+P#w[=aconFTi8>Tg]|m.+B1.Mu +kMD8MieKj&qfLvaY Ď ur eƀଃY5cef.p7z-yi^x}j#6z1^AL-Hǔ:?kY&Nph5kӄ1 Yī՚}ZfDG'1Yuұ>.P!Rxx` X⚺(X\|rW$N2[VU%N{vӷhmeH]l!C_yR弧>gJ]̴8%j8q8j^Tm?V X#O,5 aIT-|G w%AXku.{j5`[5< u?)[*h%2H[efwM7j3\DAԺuXs#x\D`-=5Su2mLeF+baY}AJNÃZ .n8#1;w9ûX< $: \q )ZXkmz+^tɥrIPΜBqHP’H#i}-) MDRA~Iu5JKuJԉnbVm:n[ kXM\wf|,<}k/YinmYQS%P=[+1&\<{VWc^)<$k;PS)ן$Z~hX֗5>霻bhg氈IAl$}+[v޸-W5Iͭ!VND8KKvz072|gsZYLsi1eCVaXwýH OUKΩg:tEcb_INO#ε7vh 5oK^oc>@yUEy3mHZ@#,M ;u!(?y *BN(DOZ|v9SFBJR!)JP)BJR!*];5w}j%Mxm+xZD/;9b*0JR׬n{2ia]Jq[[e:;I% C-(Ԟf{2Yjqp$C_<}9o* jRekCyZGy