JFIFPhotoshop 3.08BIM@Nationwide Study Examines Comorbidity Burden Predicting Three-Ye720260821PSCIENMAGUAuthorpNationwide Study Examines Comorbidity Burden Predicting Three-Year Neurodevelopment in Extremely Preterm Infants Science@https://scienmag.com/nationwide-study-examines-comorbidity-burde© 2026 Sciencehttps://scienmag.com/Extremely premature birth can leave infants facing a complicated web of medical challenges, but a new nationwide cohort study is examining whether those challenges can be measured more accurately—and used more effectively to predict children’s development years later. The research, led by Ishida, Nakanishi, Iitsuka and colleagues, focuses on neurodevelopmental outcomes at age three in […]ScienceMedMedicineMedicine'assessment of morbidity scoring methods6clinical implications of comorbidity burden assessment/comorbidity burden in extremely preterm infants@impact of early-life medical complications on childhood developm%long-term neurodevelopment prediction1medical challenges in extremely premature infants0nationwide cohort study on preterm infant health3predictive models for neurodevelopment at age three)preterm birth neurodevelopmental outcomes:prognosis of neurodevelopmental delays in preterm children+significance of specific neonatal illnesses+weighted versus unweighted morbidity scoresC    !'"#%%%),($+!$%$C   $$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$"7!1AQ"aq2R#B$34S(!1AQ"2aq4 ?i Oy-;8h$6ڒ;W5RstcU+I٠w)6"`RqE=o%A(oJx .*|&L@ >)վ*rW%Ĕ4=gm&&GˍjW5uTԝ?z_5[P_o+Rp;怙Q068:(t/3]ؐc뎮O*8\TU4* pj;n6'&˂BK;AUTJ]lOvIlS`l˞iI'qGt& ":= SPKR{t0S,q?*B|c E>:d ڦ't"S5\@yHkUyRmҶYP sRξ RB0sT'J)I̔C m!DʁAo= =sEԃN:S\ #|jZPp_0ǩ>hBhR:z P2ԍZcZȘ< ׈R6U,XCjC?;IZ<(Į C]GQO۵}\fQ2K)膟M#GV΢QBWKmE9wp`zI;У@ibȆ4c(zI3cZc' .ur%o&lSMH!HOC9]vPk1gط/66 WOw>Z"]j2y%x%U9hc47aJ正q4g\ZNa˥k;ԧ6~hX˾<JIȤoި[D-r]XHnCg*Wz|Ԡ $PjuRW$<YkUt w\ՙYQCL !g8$7=@NEpr&:Hm1]SƙEϠr="l5*O \qJ<(HܚfzQ [2}(K-պ+rjjZ,j`9cq*|*K@)R j呑ڂ=u Y博,%H=뺜JiJ-ϋjyPN] OG!E[PlD5jJTڏZS* `5*P# EH=6 ,ܤT%qn`C8a4iw7|0(U}S0 ZaAf[jjl>8Heuɚ&ˉ\sOZm8qEy%[9g'7 L]1me> csCm;yjzqX_f/GqQ>=GjK5^Plrҡ 3fT^HHڲo˚e/gyϠQAéB8Bj4LO1fpu*$mC#ZF8o80eRF uiR<l=xL 2lʳƍmҝ'ЊIA^78V9NHܨw4~?eۜbAGu(g?~]jjq0RGz_M_\{}3  ~t{hJe'2"uP~qJ>vxF'|V)zM((VNҋlh$#@m:DV9X<5/PJ° 1)S̶hÌRu<Q1 qd>ԧ}XF.4N<קR556ifUM5ek=.5ܜFpM68).-mҒkee ZeZڹCP$  -GsqrpyOJ<\ĀNީ{T0<*>ޅΚT5[J\*e<¨_zdWJFRꚀ{ԥPdjV# i|q}q#s+c*;t?z&` -"8J #lUйܷ@Žp؉kҒX=FGnɍ<⾦֕ 9r>t?G D!xԴ]#*8߄fKΨ(xJo[ I} pnY^R)'ddi_4ҳjV?:]nOY;2H[sڅjOp&YXl}cնn9Ga{GOJrc\yIZ}x=a]@2<2x7q T[up$;!jÍTZt됛[+)999m7jk2TH,H, ,pϸs|niC u $}Fc|;es #57yww-Z>/%,GvCģĢxje}CoX @q[NZ-s[ *֒hJQ 5vA?pxV1Z켒piR~vp:˩a[Dd$Rti?S!%;%)OM&B)g*޹v MsILWRUHJFHN~fкI&Qr&S $S ޞĦjHk:SBN⾈]W%M?'Tp=" tX8LgԃDbd:@pWyEBN7o2n;)]Бe| ImISj|Kwbozm>ݵJLvP8>kGFS(I>Wq]f3K~N>Ij{דqt ޭ.0u)W/\ᙐވ5JJ~7':8Jge˂J)+Rwj褜YHY,V7\)k򔓌 $[eJpr\oҭiEQui7W5|DXZD0D`Р}e-sڊF Nfd60H*-kHBR ymGZ;$ |w<.)tZ,m %8ի>XJk@~uM^r_/n cs􎍰 ȮB:Pn$U$2k !)U=܊_][ϽqUd!T