JFIFPhotoshop 3.08BIM@VESALIUS-REAL study reveals lipid treatment gaps in high-risk pa720260904POphelia KeatingUAuthorjVESALIUS-REAL study reveals lipid treatment gaps in high-risk patients lacking prior cardiovascular events Science@https://scienmag.com/vesalius-real-study-reveals-lipid-treatment© 2026 Sciencehttps://scienmag.com/lA landmark study spanning three continents and more than 1.1 million patients has revealed that people at high risk of a first heart attack or stroke are routinely left untreated, untested and off-target when it comes to their cholesterol, exposing one of the largest and most consistent gaps between cardiology guidelines and everyday clinical practice […]ScienceMedMedicineMedicine"atherosclerotic disease managementcardiovascular risk assessment&global cardiology practice disparities$guideline adherence in lipid therapy!high-risk cardiovascular patientsLDL cholesterol targetslipid treatment gapslipid-lowering therapy underuse'preventing first heart attack or stroke!real-world cholesterol managementuntreated high-risk patientsVESALIUS-REAL studyC    !'"#%%%),($+!$%$C   $$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$$"9!1A"Qaq#2B$3R4SbCr3!12AQ"aq#435BRS ?*iH^2O:$ [0kQuk!wR6@8!Fbl "Oh/!Q'l2븦n jp’:oā tC[ĐgCs&[aH!@0/E)d1~D!%R*#JTG hpUVy*B2W/U8M$5(Zn;|0psD/=׼2(g=^n{坝Ǹo:YBkwZ>"*2 J0dՂ7Pn R䊕d]lHSE,1\J RֆgQRjP3ElTԍpQruߺ7)$4@>Rz6< =I#"]ڲ}u#%!~̦@޽pe)-^4O n;aVyÍʞu!y>.986 T$%[ uX }ف󸮟e&pr BּkmR4No-~~%e]>].r$u7kd:Ko 7ke7_,K= T>kCJ}'1{-V,F1BZ{v>TorfҝC(.iv|JPj"SKm =Ϡ޺_qE{q[SSBSV>W 0G5=pB@.Uۢ8U44J )].mT Kd7#Tz$y3֛O@!+85KNWOxasP~RBkIz+TE-tzVK\v!$ڼq婋 xܨF/r]Ƒr=֙k!_V޾Tyoqp0eipǷ"hIqG8X+e{[ji^$kֈ亃$Uq?%6XKXwN [M($R+Sn) 9)8 |xA lt擖:z橕|.td<>8!m%_¥lʥG#lJWG-(PWTZ*n{gu(tgT  uJF-eyڔuϩq[J;=,nksm: G= 9a_Eՠ : + K?v?(\q$Hqc!?/zuNͼGm IBFU?uuHZwVNRYk/V}9m[\rW '0[iSnF{\51%=iwRB=ݚyx2@ָ'J6b5ΥѦO`@ 8:{5"ҭ<FTÞ^Ԓ*a!]RpiG-8Kx!iVNsZI%Eb%$vUՆ겐P z.%yZ tYmRAf)lִԊRP۵CmP˼6i[S* ej $yv2xUV!ilt1`%J@t*;lf,-8ɠeIP9[eNY5{S{ %mzŶi62h_hj@7[ij^#a,=ԗ+LRzut;rY@;gV}{/q'ÔRmhw-+tE.~D%D'1DM}GS!KHP#`T7iD`R]t+>`U"L4pj܁Df0Nm*=;zkF׿:uB52'W$ >V3*S(Rt(lqj\l>4umWej ]p6LzєÍ+<ڔ Wn~ƻU-)DtA$1n:*'J8]ԗU ;R.65ם+49Ү ĒI*WC:(;]9Jm)94dLT2lE`F*U\Vdwdճ1_2-]3BYmĪ"s]Y^Q%pdiRD&)]-4vQFye)rO=ꤛ;> Ts; h4X?\Br 8̤{]#I!?q´<+.4)dv1pj28O?L;?'TJ̗U9|cKXTXJyiPA8={.Zun揌65 ?j7sɵܛ Fۉ!v;R bb)!>DR{-l!Y51r\(jWnV0`:o,'+=3ZJB=2ٙA&v}I ]Q';%>dCNT]겺]?d8.[umQE mkƙu{8G9,:${hO+Z\dvrV@.x{UUByt.m(RTF%T>P3v8f(J77LÉuY#l͖\kprIqO5:v Rq k[`#@%A#~(0;$PU緆¨ 堡gn_4ơTItIߐQ%u&Fk)%s^C E';.y`Jї DHm-d2{f]6` )}rPpGRykZZVfMcqf['9~脺ҹBwIO:S꣚¼5eEnO0 ߂~#β!6#j^ܕ-m]S\ȶ ܘ#KO4};q\ؤ7U&lS;OŷvtnJF/l[\kDee W#̙HS'8^f;nF5_I`0R}Ywk DxUچBA\ -x-cH{rr沒#nTTġhua)QbVJ u#vH3/sWjRPȪV$޲Bs4q2h7ҘCh(q;&jUR@ ڒ!!+lRJ[RkUH5D ҌՋ$T,ijɒL(1.6k%[frM1nAƼ𚤔@ ݭILj-{i0ʓPyl h2;[?`\kjQAR֑0kVEXuӚڵ4<N(ʾFX,mԎ'~{)ei[S+: ]/c0II$nje4].ŪکwdvR W&3.4'mRFT*/ِ2ӊw&0:FZ*vЍ y Ӗ|v^TRKƶJJ+ gدz;oJ*~u^.zSR66Zʕ(RV@i3dyT^'0~FO`$`zROJMOC~V oR:NUEޣ_xR}L/*wޥJe&K RJ