Posted inGenetics
Experimental Drug Boosts DNA Repair Response in Damaged Heart Tissue
A new paper published in Science Translational Medicine describes an experimental drug capable of repairing DNA damage caused by disease. Developed…
Posted inGenetics
C3 Glomerulopathy Treatment Breakthrough Found in Complement Inhibitor
The complement system is an innate immune response that leads to increased inflammation. The drug pegcetacoplan—a complement inhibitor—was approved for…
Posted inGenetics
eXmoor Pharma and UCL Collaborate to Accelerate the Advancement of Cell and Gene Therapies
Credit: Wildpixel/Getty Images CDMO eXmoor Pharma and the Translational Research Office (TRO) at University College London (UCL) formed a strategic…
Posted inGenetics
Antibiotic-Induced Microbiome Metabolites May Trigger Antibacterial Immune Response
The microbes inside our bodies not only help break down food but also impact our health. Yet their precise influence…
Posted inGenetics
The Case for Endogenous Tagging
Sponsored content brought to you by Overcoming artifacts and capturing an accurate view of protein dynamics Understanding how proteins behave…
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The Protein Bottleneck: Why Discovery Slows Before It Starts
Sponsored content brought to you by Scientific progress often stalls not because of a lack of ideas, but because of…
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AI “Smoke Alarm” Could Detect Culture Contamination Earlier
Artificial intelligence (AI) could help biopharmaceutical manufacturers detect contamination in cell cultures sooner than conventional approaches, thereby helping to reduce…
Posted inGenetics
Bioprocessing Advances Push iPSC-Derived Neurons Toward the Clinic
Efforts to efficiently manufacture human neurons from induced pluripotent stem cells (iPSCs) are rapidly transforming the landscape of neuroscience research,…
Posted inGenetics
Formulating at the Right Structural Resolution
Biologics manufacturers need to consider the structural resolution of their formulation models to avoid overly time-consuming calculations. That’s the key…
Posted inGenetics
Automatic Microscale Antibody Purification Cuts Time and Costs
As monoclonal antibody (mAb) titers increase to multi-gram-per-liter ranges, downstream purification is increasingly strained. Protein A affinity chromatography is the…