Posted inGenetics
Epitope Editing Strategy Could Enable Less Toxic Stem Cell Transplants
Credit: JUAN GAERTNER/ SCIENCE PHOTO LIBRARY/ Getty Images Stem cell transplantation and gene therapy are among the most powerful curative…
Posted inGenetics
Fujifilm Selected with Six Others in FDA PreCheck Pilot Manufacturing Program
Credit: Fujifilm Biotechnologies Fujifilm Biotechnologies reports that its commercial-scale cell culture manufacturing facility in Holly Springs, NC, has been selected…
Posted inGenetics
Oligonucleotide Therapeutic Industry Readies Itself to Move to the Next Phase
Synthetic oligonucleotide therapeutics are now validated for treating a wider range of diseases and, as companies move to larger-scale development,…
Posted inGenetics
Perfusion Technologies Gain Momentum in Biomanufacturing
Perfusion-based manufacturing is gaining traction across the biopharmaceutical industry as companies seek to boost biologics output, improve product quality, and…
Posted inGenetics
Plant Expression Platforms May Be Better Option for Biopharma in the Global South
Mammalian cell-based manufacturing systems cannot meet the needs of the Global South, say researchers, who suggest that local production with…
Posted inGenetics
Local PBMC Isolation Enables Four-Hour Processing in San Diego
Fast, local cryopreservation is a consistent bottleneck for autologous cell therapy developers, even in major cell and gene therapy hubs.…
Posted inGenetics
Interface Mismatches Remain Key Barrier to Continuous Bioprocessing
Achieving end-to-end continuous bioprocessing without introducing surges and pooling remains a goal for biomanufacturers. As they transition from vat to…
Posted inGenetics
Astrocytes Preserve Memory Persistence Through Ankyrin-2 Protein in Mice
The main cells of the brain: yellow: neurons; orange: astrocytes; gray: oligodendrocytes; white: microglia [selvanegra/Getty Images] Although scientists have long…
Posted inBiotechnology
‘How did they get there first?’ Biotechs forced to learn new patent tricks to protect pipelines
For a biotech, your intellectual property is your most prized asset. But a new era of increased global competition means…
Posted inBiotechnology
FDA halts release of new drug rejection letters while working to formalize policy
The FDA has paused a controversial policy of releasing letters describing its rationale for rejecting drugs, Fierce Biotech has learned,…