In today’s competitive biologics and gene therapy landscape, CDMO quality control teams are under pressure to deliver faster tech transfer, reduce costs, and maintain consistently high product quality. As molecules become more complex, with AAV partial capsids, aggregates, and heterogeneous populations increasingly common, traditional analytical technologies often create bottlenecks that impact timelines and productivity.
Mass photometry (MP) is a rapid, label‑free, single‑particle mass measurement technique that provides native‑state insight into product quality in minutes using minimal sample. It can complement established orthogonal methods like AUC, delivering actionable data earlier, more frequently, and with lower operational burden.
In this GEN webinar Ray Zhang, PhD, associate director, QC-Analytics at Franklin Biolabs will introduce the principles of mass photometry and highlight where it adds value across the analytical lifecycle. He will cover operational considerations, including method robustness, system suitability, and the transition to 21 CFR Part 11 compliant workflows. He will also share a case study that demonstrates how rapid MP screening streamlines real-world CDMO QC workflows and improves overall productivity. Key takeaways from the webinar include:
- How MP compares to AUC in terms of speed, sample efficiency, and intuitive data interpretation
- QC-relevant applications of MP including lot-to-lot comparability, stability, and stress studies, and in-process or release testing
A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelist.
Produced with support from:
