Merck’s $11B anti-TL1A bet delivers 1 win, 1 loss in midphase inflammatory disease trials

A phase 2 trial of Merck & Co.’s anti-TL1A monoclonal antibody has missed its primary endpoint, closing off one avenue for expansion of an asset acquired in a $10.8 billion takeover. The setback was offset by a midphase win in another indication.