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Process intensification (PI) enhances the efficiency, flexibility, and sustainability of complex molecule manufacturing by reducing costs and increasing throughput. That is why the monoclonal antibody (mAb) industry is shifting from traditional manufacturing methods to intensified processes. In this space, PI improvements began with single-use facilities, continuous manufacturing, and upstream processing advancements aimed at boosting mAb titers and productivity. However, this shift has highlighted bottlenecks in downstream processing, necessitating a more comprehensive PI approach that spans both upstream and downstream manufacturing processes.
In this GEN webinar, Gerben Zijlstra, PhD, and Jean-Marc Cappia, both experts in process intensification, explore the significance of PI in mAb production, emphasizing its impact on productivity, sustainability, and resource consumption. They will outline innovative PI strategies, expert guidance tools, and technologies that are available to simplify PI, including continuous perfusion bioreactors, advanced membrane chromatography, and viral inactivation techniques. They will also highlight the role of data analytical tools, process analytical tools, and automation software in supporting this transition. A series of industry case studies will show how modern manufacturers leverage PI for efficient, cost-effective, and sustainable mAb production.
A live Q&A session will follow the presentation, offering you a chance to pose questions to our expert panelists.
