Posted inGenetics
Pancreatic Precancer Cells in Mice Reveal Autophagy Defects, Protein Clumps
In a twist that blurs the lines between two devastating diseases, scientists have spotted dementia-like behavior in the pancreas. In…
Posted inGenetics
Metastatic Cancers Eliminated by CD40 Agnostic Antibody
Over the past 20 years, a class of anticancer drugs called CD40 agonist antibodies has shown great promise but also…
Posted inGenetics
Schrödinger Halts Cancer Drug Program after Two Patients Die in Phase I Trial
Schrödinger has halted development of its cancer-fighting candidate SGR-2921 after two patients treated with the cell division cycle 7 (CDC7) inhibitor died…
Posted inGenetics
Antibacterials May One Day Be Derived from Ancient Archaea
Following the drive to understand and control bacteria, it’s becoming clear that our methods have changed the very organisms we…
Posted inGenetics
Protein Language Model Hits Undruggable Targets, No Structure Required
Pranam Chatterjee, PhD, assistant professor of bioengineering at the University of Pennsylvania (UPenn), emphasizes that text is all you need…
Posted inGenetics
Rapidly Evolving Human Genomic Region Tied to Neural Development, Flexible Thinking
Human-accelerated regions (HARs) are sections of the human genome that have accumulated an unusually high level of mutations as humans…
Posted inGenetics
mRNA-Based Broad Spectrum Antiviral Development Inspired by Rare Immune Disorder
Inspired by a rare immune disorder, researchers headed by a team at Columbia University have created an antiviral with an…
Posted inGenetics
Synthetic Metagenomic Method Uncovers Genetic Drivers of Antimicrobial Resistance
Antimicrobial resistance studies often focus on individual protein variants, neglecting broader protein family dynamics. Dihydrofolate reductase (DHFR), a key antibiotic…
Posted inGenetics
Absci, Almirall Expand Up-to-$650M Dermatology AI Collaboration
Absci and Almirall have expanded their 21-month-old artificial intelligence (AI)-based collaboration to develop and commercialize AI-designed therapeutics for chronic and…
Posted inGenetics
AbbVie Invests $195 Million to Expand North Chicago Manufacturing Facility
AbbVie is investing $195 million to strengthen its domestic active pharmaceutical ingredient (API) production within the U.S., with the expansion…