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sandboxaq-debuts-public-database-of-protein-ligand-structures-and-binding-affinities
Posted inGenetics

SandboxAQ Debuts Public Database of Protein-Ligand Structures and Binding Affinities

June 25, 2025
Credit: Laguna Designs/Getty Images Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with…
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ai-guided-screen-enhances-beta-cell-transplant-survival
Posted inGenetics

AI-Guided Screen Enhances Beta Cell Transplant Survival

June 24, 2025
Credit: STEVE GSCHMEISSNER/ Science Photo Library/ Getty Images Can we predict—and prevent—why transplanted beta cells fail? A preclinical study titled…
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mitochondrial-base-editing-corrects-pathogenic-mitochondrial-dna-in-patient-derived-disease-models
Posted inGenetics

Mitochondrial Base Editing Corrects Pathogenic Mitochondrial DNA in Patient-Derived Disease Models

June 24, 2025
Credit: wir0man/Getty Images In a step toward treating mitochondrial diseases, researchers at the University Medical Center Utrecht and their colleagues…
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Posted inGenetics

Epigenomic Tools for Decoding Drug Mechanism of Action

June 24, 2025
Broadcast Date:  Thursday, July 17, 2025Time:  8:00 am PT, 11:00 am ET, 17:00 CESTAs drug developers turn toward more targeted…
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organ-chip-als-model-uses-patient-ipscs-to-uncover-early-disease-progression
Posted inGenetics

Organ-Chip ALS Model Uses Patient iPSCs to Uncover Early Disease Progression

June 24, 2025
Credit: Dr_Microbe/Getty Images Amyotrophic lateral sclerosis (ALS) remains one of the most devastating and biologically elusive neurodegenerative diseases. Despite decades…
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age-related-macular-degeneration-slowed-by-increasing-apolipoprotein-m
Posted inGenetics

Age-Related Macular Degeneration Slowed by Increasing Apolipoprotein M

June 24, 2025
Fixing problems with cholesterol metabolism might help slow or prevent a common cause of age-related vision loss, a new WashU…
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brain-receptor-structure-revealed-to-support-cerebellum-function-repair
Posted inGenetics

Brain Receptor Structure Revealed to Support Cerebellum Function Repair

June 24, 2025
Neurons [BlackJack3D / 1495440392 / E+] The brain’s cerebellum plays a key role in coordinating movement, balance, and cognition. Injury…
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scientific-data-crisis-holds-back-cmc
Posted inGenetics

Scientific Data Crisis Holds Back CMC

June 23, 2025
Credit: Kobus Louw/Getty Images A biopharmaceutical industry executive recently shared a telling insight with one of my colleagues. He said…
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rare-gene-mutation-delays-alzheimer’s-by-damping-immune-cell-inflammatory-signaling
Posted inGenetics

Rare Gene Mutation Delays Alzheimer’s by Damping Immune Cell Inflammatory Signaling

June 23, 2025
Pathological phosphorylation (yellow) of Tau proteins (red-orange) by kinases (violet) leads to disintegration of microtubules in the neuron axon. The…
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potency-assays-in-cell-and-gene-therapy:-strategies-for-manufacturing-and-regulatory-success
Posted inGenetics

Potency Assays in Cell and Gene Therapy: Strategies for Manufacturing and Regulatory Success

June 23, 2025
Gregory Russotti Chief Technology and Manufacturing OfficerCentury Therapeutics Panelist Gregory Russotti Gregory Russotti is the Chief Technology and Manufacturing Officer…
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