Posted inGenetics
Microscale Chromatography Moves Toward Manufacturing Readiness
High-throughput chromatography has become a familiar tool in early bioprocess development, where parallel experiments can save time and precious material.…
Posted inGenetics
Novartis Shares Slide After Neuromuscular Candidate Acquired with Avidity Fails Phase III Trial
A process operator performs process operation in a biosafety cabinet at Novartis' manufacturing facility for innovative cell and gene therapies…
Posted inGenetics
NRAS Mutations May Require Mutation-Guided Combination Therapies
Melanoma, cells, illustration. [Artur Plawgo /Science Photo Library / Getty Images] For decades, RAS proteins have occupied a frustrating place…
Posted inGenetics
The Multi-Attribute Method (MAM) as a Biologics Lifecycle Backbone
Sponsored content brought to you by Surprises that delay manufacturing programs tend to arrive late in the day. A comparability…
Posted inGenetics
ADCs, mAbs, CAR Ts: One Bioluminescent Platform Measures Them All
Sponsored content brought to you by The development and use of biologic-based immunotherapies is one of the fastest-growing areas in…
Posted inGenetics
AI Drug Discovery Hits a New Bottleneck: Experimental Validation
Sponsored content brought to you by Artificial intelligence is dramatically accelerating early drug discovery. Models can screen chemical space, predict…
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Targeted Lentiviral Delivery Without Vector Reengineering
Sponsored content brought to you by VSV-G is the surface glycoprotein of the vesicular stomatitis virus. VSV-G-pseudotyped lentiviral vectors are…
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ProBioGen Grants Transgene Additional License for AGE1.CR.pIX Cell Line
ProBioGen’s cryostorage facility for its AGE1.CR.plX cell line. [ProBioGen] ProBioGen and Transgene report that they broadened the scope of their…
Posted inGenetics
Anticancer Candidate Strengthens Bones and Prevents Weight Gain in Postmenopausal Mice
Credit: Science Photo Library / Steve Gschmeissner/Getty Images The results of a preclinical study by researchers at the University of…
Posted inGenetics
Regenerative Medicine in the Bronze Age: MSCs and MSC-EVs Leading the Way
Sponsored content brought to you by Immunotherapies have dominated cell and gene therapy for the past 5–10 years, but the…