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gen-editors-reflect-on-six-of-the-biggest-stories-of-the-year
Posted inGenetics

GEN Editors Reflect on Six of the Biggest Stories of the Year

December 4, 2025
Credit: wenjin chen / Getty Images For the scientific enterprise, 2025 was marked by setbacks and challenges. But scientists are…
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designer-proteins-take-shape
Posted inGenetics

Designer Proteins Take Shape

December 4, 2025
With the advent of AI-powered protein design tools, protein-based therapeutics may no longer be constrained by the limits imposed by…
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beyond-vaccines:-scaling-the-promise-of-rna-therapeutics
Posted inGenetics

Beyond Vaccines: Scaling the Promise of RNA Therapeutics

December 4, 2025
As RNA therapeutics evolve far beyond their vaccine origins, a new generation of scientists and manufacturers is rethinking how to…
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painting-a-bull’s-eye-on-undruggable-cancer-targets
Posted inGenetics

Painting a Bull’s-eye on Undruggable Cancer Targets

December 4, 2025
Can all cancers become treatable and metastatic disease be halted in its tracks? Many companies share the goal of ensuring…
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industrializing-small-batch-rna-based-therapeutics
Posted inGenetics

Industrializing Small-Batch RNA-Based Therapeutics

December 4, 2025
With the question of immunotherapeutics’ efficacy answered in the resounding affirmative, the challenge has shifted to the practical considerations of…
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primary-packaging-materials-for-parenteral-products
Posted inGenetics

Primary Packaging Materials for Parenteral Products

December 4, 2025
Figure 1: Examples of Primary Packaging Material Options for Parenteral Drug Products. Primary packaging material (PPM) refers to the material…
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experimental-drug-boosts-dna-repair-response-in-damaged-heart-tissue
Posted inGenetics

Experimental Drug Boosts DNA Repair Response in Damaged Heart Tissue

December 4, 2025
A new paper published in Science Translational Medicine describes an experimental drug capable of repairing DNA damage caused by disease. Developed…
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c3-glomerulopathy-treatment-breakthrough-found-in-complement-inhibitor
Posted inGenetics

C3 Glomerulopathy Treatment Breakthrough Found in Complement Inhibitor

December 3, 2025
The complement system is an innate immune response that leads to increased inflammation. The drug pegcetacoplan—a complement inhibitor—was approved for…
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exmoor-pharma-and-ucl-collaborate-to-accelerate-the-advancement-of-cell-and-gene-therapies
Posted inGenetics

eXmoor Pharma and UCL Collaborate to Accelerate the Advancement of Cell and Gene Therapies

December 3, 2025
Credit: Wildpixel/Getty Images CDMO eXmoor Pharma and the Translational Research Office (TRO) at University College London (UCL) formed a strategic…
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antibiotic-induced-microbiome-metabolites-may-trigger-antibacterial-immune-response
Posted inGenetics

Antibiotic-Induced Microbiome Metabolites May Trigger Antibacterial Immune Response

December 3, 2025
The microbes inside our bodies not only help break down food but also impact our health. Yet their precise influence…
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