Posted inGenetics
Targeted Protein Degradation Broadens Its Scope
Like any complex system, the cell depends on a tightly regulated quality control network to maintain order and prevent the…
Posted inGenetics
Organ Chips Move Towards Mainstream Drug Development, with Hurdles Ahead
In April 2025, the U.S. Food and Drug Administration (FDA) released a strategic roadmap to make animal testing the exception…
Posted inGenetics
State of the Diagnostic Industry: Recombinants on the Rise
Discovery of a fragile foundation Four years ago in GEN, Scripps Laboratories predicted that the clinical diagnostic industry was on…
Posted inGenetics
Next Generation Biopharma Innovation
Researchers are digging deeper into biology’s complexity. In preclinical research, the traditional in vivo models are simply not enough to…
Posted inGenetics
The Confidence Gap: Why Drug Discovery’s Data Explosion Hasn’t Solved Its Billion-Dollar Decision Problem
Laurence Arnold, PhD Head of R&D Pelago Bioscience We’ve never had more data in drug discovery. Yet despite this explosion…
Posted inGenetics
Novel Therapeutic Modalities Target the Undruggable
From small molecules and protein therapeutics to gene therapies, biotech industry players have placed their bets on a wide range…
Posted inGenetics
Mass Spectrometry’s Discovery Revolution
Mass spectrometry (MS) has quietly undergone one of the most consequential evolutions in modern drug discovery. Once viewed primarily as…
Posted inGenetics
Macrocyclic Peptide Drugs Unlocked, Membrane Permeability Screened at Scale
Membrane-permeable cyclic peptide that inhibits the intracellular Keap1-Nrf2 protein-protein interaction. [Christian Heinis (EPFL)] Macrocyclic peptides are a promising drug modality that combine the oral convenience…
Posted inGenetics
Multiomics Mass Spec Workflows in Drug Discovery
Credit: Jose A. Bernat Bacete / Getty Images Advances in end-to-end multiomics platforms and the underlying scientific knowledge now enable…
Posted inGenetics
One Antibody, Fewer Scientific Surprises
Sponsored content brought to you by In biomedical research, promising programs rarely collapse for lack of scientific ambition. More often,…